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Researchers have obtained images of the NMDA receptor in active, non-active, and inhibited states. Understanding how NMDA receptors activate is critical in designing novel therapeutic compounds for schizophrenia, depression, Alzheimer's and other illnesses.
http://dlvr.it/LCXczN

The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva, a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms. The study identifies a…
http://dlvr.it/LCXct7

Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report.
http://dlvr.it/LCXcrR

Children with Attention Deficit and Hyperactivity Disorder follow fewer healthy lifestyle behaviors than non-ADHD youth. ADHD youth may benefit from improving lifestyle choices such as increasing water consumption, decreasing screen time and getting at least one hour of physical activity per day.
http://dlvr.it/LCXcqB

Small changes in the social lives of older people are early red flags showing that their thought processes and brain functioning could be on the decline.
http://dlvr.it/LCXcm1

Individual small RNAs are responsible for controlling the expression of gonadoliberin or GnRH (Gonadotropin-Releasing Hormone), a neurohormone that controls sexual maturation, the appearance of puberty, and fertility in adults, new research shows. The involvement of microRNAs, transcribed from DNA,…
http://dlvr.it/LCXchy

The primary method used to test compounds for anti-cancer activity in cells is flawed, researchers report. The findings cast doubt on methods used by the entire scientific enterprise and pharmaceutical industry to discover new cancer drugs.The researchers have developed a new metric to evaluate a…
http://dlvr.it/LCXcCB

The combined incidence of serious infection, the intestinal disease necrotizing enterocolitis and death was similar in very low-birth-weight infants who received either pasteurized donor milk or preterm formula supplementation during their first 10 days of life when their own mother's milk was not…
http://dlvr.it/LCXNYC

A 25 percent calorie restriction over two years by adults who were not obese was linked to better health-related quality of life, according to the results of a randomized clinical trial.
http://dlvr.it/LCXNTf

Concussions in high school football had the highest average number of reported symptoms and high school football players had the highest proportion of concussions with a return-to-play time of at least 30 days compared with youth and college players, according to a new article.
http://dlvr.it/LCXNRZ

A new study has identified two self-regulation strategies effective in preventing weight gain among young adults. At the end of the three-year study, researchers showed that young adults taught self-regulation strategies were more successful at preventing weight gain than those in the control group…
http://dlvr.it/LCX5vt

The stereotypes we hold can influence our brain's visual system, prompting us to see others' faces in ways that conform to these stereotypes, neuroscientists have found.
http://dlvr.it/LCX5fY

Follicular helper T cells (Tfh cells), a rare type of T cells, are indispensible for the maturation of antibody-producing B cells. They promote the proliferation of B cells that produce highly selective antibodies against invading pathogens while weeding out those that generate potentially harmful…
http://dlvr.it/LCWHT6

The largest-ever study to sequence the whole genomes of breast cancers has uncovered five new genes associated with the disease and 13 new mutational signatures that influence tumor development. Two new studies pinpoint where genetic variations in breast cancers occur. The findings provide insights…
http://dlvr.it/LCVjMn

Buprenorphine is a critical part of treatment for the growing epidemic of opioid abuse -- but also carries the potential for misuse and diversion. The debate over whether 'to expand or not to expand' prescribing of buprenorphine for opioid abuse is discussed in a new expert review.
http://dlvr.it/LCVQjB

No added benefit has been proven for chronic lymphocytic leukaemia and Waldenström macroglobulinaemia. Certain patients with relapsed or refractory mantle cell lymphoma benefit from the drug.
http://dlvr.it/LCVQRV

Using an ultra fast-scanning atomic force microscope, a team of researchers has filmed "living" nuclear pore complexes at work for the first time. Nuclear pores are molecular machines that control the traffic entering or exiting the cell nucleus. In a new article, the researchers explain how the…
http://dlvr.it/LCVBjW

One of the skeletal markers that anthropologists use to decipher the past, linear enamel hypoplasia, might need to be looked at in a new light. Scientists show that LEH, a result of stress during an individual's life, might be an indicator of good, rather than poor, health.
http://dlvr.it/LCVBdC

Ebola virus samples taken from Liberian patients in June 2015 are genetically similar to other Ebola virus sequences from Western Africa, according to new research. The study sheds light on several aspects of the 'flare-ups' that have occurred in Liberia since the country was declared free of the…
http://dlvr.it/LCVBCt

A research team has designed and synthetized a series of analogues of (-)-Englerin A that are highly selective and effective in the growth-inhibition of renal cancer cells.
http://dlvr.it/LCTpsL

In the brain, there is a delicate interplay of signaling substances and cellular activity. Scientists have now identified another key player within this ensemble. In a laboratory study they found that the 'cannabinoid type 2 receptor' influences information processing inside the hippocampus. The…
http://dlvr.it/LCTphT

Nurturing stem cells atop a bed of mouse cells works well, but is a non-starter for transplants to patients. Instead, scientists are developing a synthetic bed.
http://dlvr.it/LCRtQ6

Students at New York City high schools in Harlem who learned about the failures and personal struggles of famous scientists scored significantly higher on STEM tests than those who did not. The scores of struggling students rose more than those of successful students, according to a new study.
http://dlvr.it/LCRtQ3

Depression symptoms that steadily increase in older adults are more strongly linked to dementia than any other types of depression, and may indicate the early stages of the disease, according to the first ever long-term study to examine the link between dementia and the course of depression.
http://dlvr.it/LCRtPr

People with psoriatic arthritis have told researchers about the condition's deeply damaging mental effects and how healthcare services failed to prepare them for its reality, a new English study concludes.
http://dlvr.it/LCRtNy

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