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Researchers have conducted a review of the clinical and cost effectiveness of labor induction methods. As the number of women facing induction increases, and as new evidence from trials emerges, it has become urgent to address questions about which methods of inducing labor are most effective,…

Forensic researchers have for the first time established science-based standards for identifying human remains based on X-rays of an individual's spine, upper leg or the side of the skull.

During a randomized clinical trial, 85 participants underwent treatment for severe generalized anxiety disorder. Cognitive behavioral therapy alone was given to 43 participants and the rest received a combination of CBT and MI from therapists trained in both.

Understanding the sequence-structure-function relationship -- the 'protein folding problem' -- is one of the great, unsolved problems in physical chemistry, and is of inestimable scientific value in exposing the inner workings of life and the rational design of molecular machines. A study lays the…

A patch is capable of non-invasive blood sugar monitoring and painless drug delivery. The device's pH and temperature monitoring functions enable systematic corrections of sweat glucose measurements as the enzyme-based glucose sensor is affected by pH (blood acidity levels) and temperature.

The largest genetic study on the bacterium responsible for epidemic dysentery has revealed that the Shigella dysenteriae pathogen, which remains a real scourge in Africa and Asia, probably originated in Europe. This research also charts the development of the pathogen's resistance to antibiotics.

Endocrine-disrupting chemicals may contribute to reproductive health problems experienced by hundreds of thousands of women, costing European Union an estimated 1.4 billion Euros ($1.5 billion) a year in health care expenditures and lost earning potential, according to a new study.

An environmental toxicologist who has been an outspoken critic of the current linear no-threshold (LNT) approach to risk assessment for radiation and toxic chemicals, now proposes a new approach integrating LNT with hormetic dose-response models. The new strategy, applied to chronic animal…

New research has demonstrated that dozens of these targeted therapies suppressed the activity of T cells that could actually help fight tumors. While studying the FDA-approved targeted therapy trametinib, the researchers also found that pairing it with a signaling protein 'superagonist' stimulated…

NCCIH Director Dr. Josephine Briggs stresses that the nonpharmacologic management of pain is a key focus of the Center's research portfolio.

Contact lenses may alter the natural microbial community of the eyes, according to a study. In a study of 58 adults seeking outpatient eye care, researchers found that contact lenses make the eye microbiome more skin-like, with higher proportions of skin bacteria.

Having coordinated care and a long-term care plan in place that considers the needs of a person with dementia may reduce unnecessary transitions, say the authors of a new study.

Researchers have devised a simple method to determine split renal function— critical knowledge for anyone planning to donate a kidney or to guide doctors' decisions for surgery and other medical treatments.

The effectiveness of e-cigarettes as a smoking substitute will likely rely on whether they can consistently provide the amount of nicotine a smoker needs to resist the desire to return to traditional cigarettes.

The more time young adults use social media, the more likely they are to be depressed, according to new research. The findings could guide clinical and public health interventions to tackle depression, forecast to become the leading cause of disability in high-income countries by 2030.

Most high-risk lung cancer patients might not need annual low-dose computed tomography (LDCT) screenings if they are cleared of disease in their initial test, according to a study.

For adults with chronic low-back pain, two mind and body practices―mindfulness based stress reduction (MBSR) and cognitive-behavioral therapy―resulted in greater improvement in pain and functional limitation compared to usual care. The randomized study, which was funded by NCCIH and conducted in…

Mindfulness based stress reduction (MBSR) and cognitive-behavioral therapy (CBT) may prove more effective than usual treatment in alleviating chronic low-back pain, according to a new study funded by the National Center for Complementary and Integrative Health (NCCIH), part of the National…

Scientists have revealed the brain activity in animals that helps them find food and other vital resources in unfamiliar environments where there are no cues, such as lights and sounds, to guide them.

A parasitic flatworm that infects hundreds of millions of people in the developing world is able to survive in the bloodstream for decades by constantly renewing its skin - a mechanism that could inform potential new treatments against infection.

New research shows that life expectancy declined significantly and rapidly in three countries where policy changes increased access to prescription opioids, alcohol or illicit drugs. The study underscores the need for effective substance use policies and public health interventions, and provides…

Researchers reveal how perceived external information is converted into a succession of neural activities that are crucial for appropriate navigation in an environment.

Researchers have discovered that the benefits of stimulating the brain with direct current come from its effects on astrocytes -- not neurons -- in the mouse brain. The work shows that applying direct current to the head releases synchronized waves of calcium from astrocytes that can reduce…

Many people believe a glass of wine with dinner will help them live longer and healthier -- but the scientific evidence is shaky at best, according to a new research analysis.

Rosy periwinkle is a plant that produces organic compounds used to treat cancer, arrhythmia, and other medical conditions. A Japanese research group has revealed the details of the metabolism process for these compounds on a cellular level. Their data suggests the existence of an unknown mechanism…

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