Articles

The addition of PD-1 antibody pembrolizumab to standard first-line chemotherapy for treatment-naïve advanced non-small-cell lung cancer significantly improves response rates and progression-free survival, researchers report.
http://dlvr.it/MQqHLB

Nintedanib improves progression-free survival but not overall survival in patients with metastatic colorectal cancer who are not responding to standard therapies, according to results of the phase III LUME-colon 1 trial.
http://dlvr.it/MQqHL7

The first phase III study of PD-L1 inhibitor atezolizumab in previously-treated non-small-cell lung cancer has seen significant improvements in survival compared to standard chemotherapy, researchers report.
http://dlvr.it/MQqHKw

The first detailed biochemical characterization of a flavoenzyme involved in antibiotic resistance has now been revealed by scientists.
http://dlvr.it/MQqHKb

African-American and Hispanic men in the United States are less likely to receive therapy for prostate cancer compared to Caucasian men — even when they have more aggressive disease, according to new research.
http://dlvr.it/MQqHJp

The bacteria Pseudomonas aeruginosa can thrive in environments as different as the moist, warm tissue in our lungs, and the dry, nutrient-deprived surface of an office wall. Such adaptability makes it problematic in healthcare -- where it causes infections in cases of cystic fibrosis, cancer, HIV,…
http://dlvr.it/MQqHFx

Ceritinib provides longer progression-free survival than chemotherapy in crizotinib-pre-treated patients with non-small-cell lung cancer harbouring an ALK rearrangement, according to results of the phase III ASCEND-5 study.
http://dlvr.it/MQWPtQ

Pembrolizumab is set to become a new option for first line treatment of patients with advanced lung cancer and high PD-L1 expression, according to the results of the phase III KEYNOTE-024 trial.
http://dlvr.it/MQWPqK

Nivolumab maintains function and reduces symptoms in treatment of relapsed metastatic head and neck cancer, according to results from the CheckMate 141 trial.
http://dlvr.it/MQWPJ5

A nationwide study of head and neck cancers in France has revealed that the true burden of the disease is underestimated by at least one-third, and that head and neck cancers carry a very high risk of secondary primary cancers, according to research.
http://dlvr.it/MQVzsg

Seven out of ten patients with advanced cancer receive a palliative care consultation at ESMO Designated Centres of Integrated Oncology and Palliative Care, according to survey results.
http://dlvr.it/MQVzsV

The PARP inhibitor niraparib significantly improves the outcome of platinum-sensitive recurrent ovarian cancer, according to full data from a trial. The trial met its primary endpoint, with niraparib considerably prolonging progression-free survival compared to placebo.
http://dlvr.it/MQVzsL

The first-in-human dose escalation study of the pan-FGFR (fibroblast growth factor receptor) inhibitor BAY 1163877 in patients with treatment-refractory locally advanced or metastatic solid tumours were reported today at the ESMO 2016 Congress in Copenhagen. The novel compound uses messenger RNA…
http://dlvr.it/MQVzsG

The addition of the CDK4/6 inhibitor ribociclib to letrozole therapy significantly improves progression-free survival in postmenopausal women with hormone receptor-positive advanced breast cancer, researchers report.
http://dlvr.it/MQVzs8

Fulvestrant significantly increases progression-free survival in women with hormone-receptor-positive advanced breast cancer, particularly those with less aggressive lower-volume disease, researchers report.
http://dlvr.it/MQVzrv

Ipilimumab as adjuvant therapy significantly improves overall survival in patients with high risk stage III melanoma, according to the EORTC 18071 phase III trial results.
http://dlvr.it/MQVzrf

Immunotherapy has shown promising results in first and second line treatment of metastatic bladder cancer in two phase II trials.
http://dlvr.it/MQVzqQ

A new survey of children's and teenagers' eating habits at fast-food restaurants suggests that consumption levels of sugary drinks are closely tied to their automatic inclusion in "combo meal" packages.
http://dlvr.it/MQVzm1

As the NHS lurches from crisis to crisis, the UK's approach to health needs radical rethinking to create a healthy and health-creating society. Just as the founding of the NHS in 1948 was a great national movement creating a health service for everyone, today all sectors of society – from…
http://dlvr.it/MQVzdy

A team of cancer specialists and health economists have developed a tool that can measure a patient's risk for, and ability to tolerate, the financial stress associated with treatment.
http://dlvr.it/MQFVlp

PTSD experts agree that the condition has its roots in very real, physical processes within the brain – and not some sort of psychological "weakness". But no clear consensus has emerged about what exactly has gone "wrong" in the brain. A new theory that integrates decades of research focuses on a…
http://dlvr.it/MQFVlj

Leading-edge research has shown for the first time that a malfunctioning stress-coping mechanism in the brain is at the root of Parkinson's disease. Genetic mutations that cause Parkinson's disease can prevent synapses – the junctions between neurons where electrical signals are transmitted – from…
http://dlvr.it/MQFVlg

New research reveals endoglin as a critical factor in determining the fate of early undifferentiated cells during development. Endoglin, a receptor involved in cell signaling, has previously been known mostly for its function in blood vessels and angiogenesis. Researchers showed endoglin modulates…
http://dlvr.it/MQFVlf

Using online social media does not lead to long-term problems with our ability to concentrate, according to new research .
http://dlvr.it/MQFVlY

Mathematical modeling of the brain scans of patients with Alzheimer's disease and others at risk for the devastating neurodegenerative disorder has identified specific patterns of brain atrophy that appear to be related to the loss of particular cognitive abilities.
http://dlvr.it/MQFVlX