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Proteins that bind DNA or RNA are usually put in different categories, but researchers recently showed how the p53 protein has the capacity to bind both and how this controls gene expression on the levels of both transcription (RNA synthesis) and mRNA translation (protein synthesis).
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Scientists have created randomly spiking neurons using phase-change materials to store and process data. This demonstration marks a significant step forward in the development of energy-efficient, ultra-dense integrated neuromorphic technologies for applications in cognitive computing.
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Engineers have developed a microfluidic device that replicates the neuromuscular junction -- the vital connection where nerve meets muscle. The device, about the size of a US quarter, contains a single muscle strip and a small set of motor neurons. Researchers can influence and observe the…
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The results of two phase 3 clinical trials that led to FDA approval of adalimumab for treatment of the chronic inflammatory skin disease hidradenitis suppurtiva are now being published. An inhibitor of the inflammatory protein tumor necrosis factor, adalimumab is the first such medication approved…
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CaptiView is a microscope image injection system that overlays critical virtual reality imaging directly onto the brain when viewed through the eyepiece during surgery.
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A new generation of drugs that prevent cancer and Alzheimer's could be developed, thanks to a new database of the proteins needed for autophagy.
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Twitter users who are happy tend to be more connected with other happy users. This is the confirmation of a property of social networks known as assortativity: a measure of to what extent people who tend to connect with each other share certain characteristics. A study has redefined this measure in…
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Lung cancer is the most common cause of cancer deaths. Adenocarcinomas, a non-small cell lung cancer, account for about 40 percent of cancer diagnoses, but available treatments are limited. Researchers have identified a subtype of human adenocarcinoma. The research could help determine individuals…
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Researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer's patients. Their findings suggest there is a link between brain activity and the presence of this protein.
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The alert is out and South Floridians are taking heed. With the Centers for Disease Control and Prevention issuing a warning for visitors and locals to avoid a neighborhood in Miami after more than a dozen individuals contracted Zika, a new study shows how the flow of visitors through a popular…
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Minority populations have lower rates of total knee replacement utilization but higher rates of adverse health outcomes associated with the procedure, according to a new study.
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A single gulp of ocean water, or roughly three teaspoons, is all it will take for athletes and tourists to contract potentially deadly diseases at the 2016 Rio Olympics. That's the consensus of a recent study commissioned by the Associated Press looking at levels of viruses, bacteria and other…
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Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of the damage caused by blinding retinal diseases, report investigators.
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Monitoring electrical signals from muscles and nerves has become easier with a 1x1x3 mm sensor that can be implanted anywhere in the body, powered and read out by ultrasound. With further miniaturization, these sensors could replace brain electrodes wired through the skull to control prosthetics,…
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In a normal full-term pregnancy, signals from the mature organs of the fetus and the aging placental membranes and placenta prompt the uterus' muscular walls to begin the labor and delivery process. It's still unclear how these signals accomplish this goal or how they reach from the fetal side to…
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People are more likely to delegate decisions--or "pass the buck"--when faced with choices that affect others than when those decisions affect only themselves, according to new research.
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Researchers are studying a protein called Nef involved in HIV progression to AIDS with the ultimate goal of blocking it. He and his collaborators have developed a new hybrid method to study this HIV protein that compromises the immune system. The method also could work on many other proteins that…
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When slim men suffer bouts of low blood sugar, chances are that they will make unfair decisions involving the more rotund people they engage with in the workplace.
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Brain tissue can die as the result of stroke, traumatic brain injury, or neurodegenerative disease. When the affected area includes the motor cortex, impairment of the fine motor control of the hand can result. Researchers found that inosine, a naturally occurring purine nucleoside that is released…
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Researchers have discovered what causes the sleep homeostat -- a switch in our brains -- to flip and wake us up. The discovery brings us closer to understanding the mystery of sleep.
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For a cell in an embryo, the secret to becoming part of the baby's body instead of the placenta is to contract more and carry on dancing, scientists have found. The study could one day have implications for assisted reproduction.
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Outpatient cutaneous surgical procedures are common and surgical gloves are standard practice to prevent postoperative surgical site infection. But, is there a difference in SSIs when sterile vs. nonsterile gloves are used for these minor procedures? A systematic review and meta-analysis of the…
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A groundbreaking scientific study has found one way an RNA binding protein may contribute to ALS disease progression.
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In work that aims to protect soldiers, a team of scientists has created a material that is highly breathable yet protective from biological agents. This material is the first key component of futuristic smart uniforms that also will respond to and protect from environmental chemical hazards.
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Researchers have unraveled the structure and function of bacterial decapping enzyme. These structural investigations open up a new field of research, say the investigators.
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