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Chemists have significantly improved upon the synthesis of a molecule related to muscle and neuronal function. A research team has been busy trying to crack the puzzle of the insecticide ryanodine, a complex molecule first isolated from a tropical plant in the 1940s. Ryanodine paralyzes insects by…
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In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling. This process cannot be influenced by standard cortisone therapy.
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As scientists around the globe join efforts to understand brain function, we enter the era of Big Data and stir up debate on how science is done and how it can affect us all.
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Banning tobacco sales within 1,000 feet of schools could reduce socioeconomic and racial/ethnic disparities in tobacco density across neighborhoods, according to a study.
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Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment -- to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.
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A physicist has developed a novel technology that not only sheds light on basic cell biology, but also may aid in the development of more effective cancer treatments or early diagnosis of disease.
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Scientists have discovered that SynGAP and PSD-95, two abundance proteins in PSD that are known to cause autism when mutated, can form an autonomously assembled network structure both in test-tube and in living cells. The SynGAP/PSD-95 assembly can form stable 'oil-like' droplets in the midst of…
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Researchers have identified a mechanism in mice by which anticancer immune responses are inhibited within the lungs, a common site of metastasis for many cancers.
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Preventing cells of beige fat -- a calorie-burning tissue that can help to ward off obesity and diabetes -- from digesting their own mitochondria traps them in a beneficial, energy-burning state. In mice, this successfully protected against obesity and pre-diabetic symptoms, raising hopes for…
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Using a new mouse model, researchers have found that stiffer arteries can also negatively affect memory and other critical brain processes. The findings may eventually reveal how arterial stiffness leads to Alzheimer's and other diseases involving dementia.
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There is a new and emerging field of drug transporters that have the capacity to reach the brain more efficiently, say researchers, bringing together chemistry, pharmacy and biomedicine.
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A research team has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA. The technique offers, through high-level editing operation, a method to address the existing issues of genome editing. It is expected that the technique will be applied to gene therapy…
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While calcium's importance for our bones and teeth is well known, its role in neurons—in particular, its effects on processes such as learning and memory—has been less well defined. A new study offers insights into how calcium in mitochondria -- the powerhouse of all cells -- can impact the…
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Researchers analyzed an online medical forum to better understand what patients want to know about e-cigarettes and how doctors respond to those questions.
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Scientists believe a drug commonly prescribed for type 2 diabetes could be routinely taken by type 1 diabetic patients to slow the development or delay heart disease.
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Exposure to the sun may deteriorate your sunglasses over time and the lenses may become lighter and so alter the category under which they are classified. It may also diminish the impact resistance of lenses (how 'shatterproof' the lens is). Revision of standards is needed to test sunglasses…
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Ultrasound imaging is used around the world to help visualize developing babies and diagnose diseases. Sound waves bounce off the tissues, revealing their different densities and shapes. The next step in ultrasound technology is to image not just anatomy, but specific cells and molecules deeper in…
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Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of humankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says a neuroscientist.
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Functional human collagen has been impossible to create in the lab. Now, a team of researchers describes what may be the key to growing functional, natural collagen fibers outside of the body: symmetry.
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By Lisa Pecos In an age where anxiety and stress disorders are increasing and doctors are prescribing more and more antianxiety and antidepressant drugs than ever before. While this can be attributed to also living in an age where we… The post Vitamins to Treat Anxiety and Stress appeared first…
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Researchers have shown how anti-HIV protein inhibitor drugs can bind to the wrong protein, causing unwanted side effects.
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There's no need to reinvent the genetic wheel. That's one lesson of a new study that looks to the saliva of humans, gorillas, orangutans, macaques and African green monkeys for insights into evolution. The work shows that adaptation isn't just about creating new tools for survival -- it's also…
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Studies show that men are not as environmentally friendly as women. But could men be persuaded to go green? New research indicates the answer is yes — and it's all about branding.
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Globally, about 42 million people now have dementia, with Alzheimer's disease as the most common type of dementia. Rates of Alzheimer's disease are rising worldwide. The most important risk factors seem to be linked to diet, especially the consumption of meat, sweets, and high-fat dairy products…
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Researchers use evolutionary theory to make predictions about which Barrett's esophagus (BE) patients will go on to develop cancer. The results point the way toward more accurate medical assessments for patients with BE and the development of early-warning beacons of disease known as biomarkers.
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