Articles

Mini midbrains provide next generation platforms to investigate human brain biology, diseases and therapeutics, report scientists.
http://dlvr.it/LwTBr8

Scientists have developed a new method of measuring the activity of disease-causing mutations in the LRRK2 gene, a major cause of inherited Parkinson's disease.
http://dlvr.it/LwNx4y

Investigators report preclinical research showing that Krüppel-like factor 12 promotes colorectal cancer cell growth by activating early growth response protein 1. Data also reveal that levels of KLF12 and EGR1 correlate synergistically with a poor CRC prognosis. Results indicate that KLF12 plays…
http://dlvr.it/LwMqsl

Compromise always occurs among two decision makers when a woman is involved (female pairs or mixed gender pairs) because compromise is consistent with feminine norms. It hardly ever occurs when the decision makers are both men because extremism is a more masculine trait; men tend to push away from…
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Official government statistics on traffic deaths in southwest India significantly misrepresented the number of pedestrian and motorcycle deaths in the region over a two-year period, casting doubt on the reliability of that country's government data on traffic fatalities, a study suggests.
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Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I.
http://dlvr.it/LwJbwx

Researchers have developed a hybrid treatment that harnesses a monoclonal antibody to deliver antisense DNA to acute lymphoblastic leukemia (ALL) cells and that may lead to less toxic treatments for the disease.
http://dlvr.it/LwJMbz

Reducing firearm access, smart gun technology, and public education could reduce firearm suicides in the United States, finds a new report.
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A protein discovery offers a possible test for ovarian cancer, report scientists. The research team also identified an enzyme vital to ovarian cancer growth and spread, offering a target for new treatments. In ovarian cancer, early detection and treatment are vital; this research offers routes to…
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An international team of researchers has discovered the mutation responsible for a rare, newly identified genetic disorder that causes craniofacial abnormalities and developmental delays. The mutation disrupts normal protein transport within cells, shedding light on a fundamental process in cell…
http://dlvr.it/LwJ6S1

While it's a matter of conventional wisdom in popular culture that raising antioxidant levels in the body tends to keep cancer at bay, a research team demonstrates that in pancreatic cells on the road to cancer or already malignant, the last thing one wants to do is to raise antioxidant levels.…
http://dlvr.it/LwJ6RZ

Researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully.
http://dlvr.it/LwJ6Dy

Patients carrying certain mutations that cause Long QT Syndrome, a rare cardiac rhythm disorder, have an increased risk for developing seizures and have more severe cardiac symptoms.
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A discovery may lead to more close-fitting, comfortable and user-friendly prosthetics.
http://dlvr.it/Lw2Llm

As fewer teens overall take up smoking, those who do smoke daily are reporting more health complaints than in years past, a new study indicates.
http://dlvr.it/Lw2LYq

A new research replication project, involving 24 labs and over 2,100 participants, failed to reproduce findings from a previous study that suggested that self-control is a depletable resource.
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People living with HIV who naturally produce broadly neutralizing antibodies (bNAbs) that may help suppress the virus have different immunological profiles than people who do not, researchers report. While bNAbs cannot completely clear HIV infections in people who already acquired the virus,…
http://dlvr.it/Lw1TWl

The supercoiling of bacterial chromosomes around histone-like proteins can trigger the expression of genes that make the microbe invasive, new research shows. The discovery could provide a new target for the development of drugs to prevent or treat bacterial infection, say scientists.
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In a study of more than 5,000 people, investigators have found that greater intake of nuts was associated with lower levels of biomarkers of inflammation, a finding that may help explain the health benefits of nuts.
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Researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.
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A new study shows both high and low cognitive ability have distinct prejudices against particular groups.
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They may be slimy, but they are a perfect environment for microorganisms: biofilms. Protected against external influences, here bacteria can grow undisturbed, and trigger diseases. Scientists are researching how it can be possible to prevent the formation of biofilms from the beginning. On this…
http://dlvr.it/Lw1QJS

In psychiatric clinics with an exclusively open-door policy, the risk of patients committing suicide or absconding from treatment is no higher than in clinics with locked wards. This has been demonstrated in a large study in which around 350,000 cases were analyzed over a period of 15 years.
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The effectiveness of reprogramming cells into blood cells is thought to depend on the original cell type and reprogramming method. Researchers show this assumption is actually the result of epigenetic effects, suggesting any founder cell and reprogramming method is feasible for blood production.
http://dlvr.it/Lw1CLr

New research helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.
http://dlvr.it/Lw1C64