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DNA does not always adopt the form of the double helix which is associated with the genetic code; it can also form intricate folds and act as an enzyme: a deoxyribozyme. Scientists have solved the first three-dimensional structure of this biomolecule that has proved much more flexible than…

A solution for long-term preservation of cells and organs for transplant has been uncovered as part of a global alliance to bank organs. After decades of studies, scientists now believe that a breakthrough in preserving body organs for the purpose of saving lives is close at hand.

Researchers are studying the causes of premature aging of neurons in Parkinson's patients with a defective DJ1 (PARK7) gene. The genetic defect causes changes in the cellular metabolism meaning that neurons are subjected to oxidative stress and an increased immune response in the brain.

A majority of patients diagnosed with breast cancer go on to develop symptoms of post-traumatic stress disorder, and in most of these cases the symptoms persist for at least a year, new research indicates.

In the brain, patterns of neural activity are perfectly balanced. The interplay between activating and inhibitory neurotransmitters ensures that the level of activity stays within the physiological range. During an epileptic attack excitation gains the upper hand resulting in the death of neurons.…

In recent decades, obesity has become a global problem. The disease goes hand in hand with a dramatic increase in the proportion of body fat. Researchers have now succeeded in inhibiting a protein in mice that hampers activation of the useful "brown fat" in obese mice. When treated with inhibitors…

Every cell in our bodies has its proper place, but how do they get there? A research group has discovered the mechanism for a mosaic pattern formation of two different cell types. Their discovery has potentially broad applications as a common principle for determining pattern formation in different…

Injections received in the months prior to total knee or total hip replacement surgery may increase the risk for infection and related complications, according to two new studies -- among the largest conducted on this topic.

Implementing bundled payments for total joint replacements resulted in year-over-year improvements in quality of care and patient outcomes while reducing overall costs, according to a new three-year study. Specifically, researchers saw reductions in overall length of stay, decreases in admission to…

Over-the-counter moisturizers fortified with specialized nanoparticles can regulate genes that interfere with wound healing.

Outsized human suffering is linked to 'amyloid beta,' an otherwise tiny, innocuous-looking protein molecule, as it is suspected to be a key player in neurodegenerative mechanisms underlying Alzheimer's disease. The molecules appear to become toxic within our bodies when they make contact with each…

The cost of health insurance, limits in eligibility and difficulties with the application process are among the major reasons more than 200,000 individuals across Massachusetts are still uninsured, according to a new report .

Move over diet and exercise, a new weight control method is in the works and it involves manipulating the production of fat cells at their source. A new research report shows that at least some human fat cells are actually produced from stem cells that originate in bone marrow.

New research shows that a commonly prescribed class of high blood pressure drugs may have the potential to slow the growth of triple negative breast cancer tumors. These drugs, called 'beta blockers' work by counteracting the pro-growth effect caused by adrenaline by affecting the the…

Challenges in benchmarking difficult, but clinically important regions of the genome have been reported. The results underscore the need to extend benchmarking references against which sequencing data and analyses can be compared and validated.

A new study reports that current rising temperatures already noticeably load the 'climate dice,' with growing practical impacts. As a bottom line, the lead author argues that a carbon fee is needed to spur replacement of carbon fuels with clean energy.

Researchers have found habitats suitable for lone star tick populations in Kansas are growing.

A new study suggests that telemedicine-based management for obstructive sleep apnea is as effective and may be comparable to in-person care.

Transplant surgeons report that obtaining organs from deceased organ donors costs much less and leads to a higher number of transplantable organs recovered when brain-dead donors are moved from the hospital to an independent, freestanding facility dedicated to organ recovery.

A new study has examined the dietary habits of more than 18,300 US adults, and found the majority of people who increased their consumption of plain water by 1 percent reduced their total daily calorie intake as well as their consumption of saturated fat, sugar, sodium and cholesterol.

A researcher used rigorous statistical methods from the field of economics to show how small increases in social spending on welfare and education can reduce the risk of dying.

Waterborne diseases are being spread by El Niño, say researchers. El Niño describes the unusual warming of surface waters along the tropical west coast of South America. These events tend to occur every 3 - 7 years; something many suggest have become more regular and extreme in recent years, as a…

Early screening with MRIs can reduce breast cancer mortality for female survivors of childhood Hodgkin's lymphoma (HL) who received chest radiation, researchers have confirmed in a screening effectiveness study.

New research suggests that Helicobacter pylori (H. pylori) infection of the stomach, which occurs in about half of the world's population and can cause peptic ulcers and stomach cancer in minority of cases, may help protect against an allergic disorder of the esophagus condition called eosinophilic…

If your neighborhood is well-lit at night, you may not be sleeping well, according to a new study.

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