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By seeking the advice of patients, families and other stakeholders in designing a clinical trial investigating pediatric appendicitis, researchers found a way to significantly increase the number of people recruited and retained in the trial.
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Humans can tolerate the parasites responsible for the sleeping sickness, Chagas disease and leishmaniasis for many years. These parasites belong to the same family of pathogens known as trypanosomatids. Researchers have highlighted this tolerance phenomenon in humans, which results from the genetic…
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A new study is the first to demonstrate the connection between the emotions anger, contempt and disgust and hostility toward opponent groups. Study participants primed with these emotions expressed more hostility toward opponents than participants primed with sadness and fear or neutral emotions,…
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Patterns of episodes of diverticulitis before surgery, and factors associated with earlier interventions using inpatient, outpatient, and antibiotic prescription claims, have all been examined by a group of researchers.
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Newly patented compounds show significant improvements over existing treatments, showing low toxicity and, consequently, fewer side-effects. Infectious tropical diseases mainly affect people living in developing countries. They are transmitted by the bites of insects carrying parasites that are…
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Scientists have analyzed more than 500 previously published scientific articles and proposed their own approach to the choice of methods used for the treatment of one of the most common cancers.
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A number of complications are associated with diabetes, but they are more prevalent in some patients than in others. A new study has now revealed two genetic mutations which seem to lower the risk of contracting a diabetic retinal or kidney disease.
http://dlvr.it/KTXQWl

Faulty bioelectric signaling has been found to be responsible for the skull and facial abnormalities that characterize the rare genetic disorder Andersen-Tawil Syndrome (ATS). It may therefore be possible to alter bioelectrical signaling to correct effects of fetal alcohol syndrome and other…
http://dlvr.it/KTW6Ct

Combined health coaching and remote monitoring did not reduce all-cause 180-day hospital readmissions among heart failure patients, and did not have significant effects on 30-day hospital readmissions, 30-day mortality, or 180-day mortality, reports a new article. But patients reported…
http://dlvr.it/KTW683

Researchers have discovered how cells in the human body build their own 'railway networks', throwing light on how diseases such as bowel cancer work. The microtubule tracks are vital for functions such as cell division and are a key target for key cancer drugs. Now researchers are studying how…
http://dlvr.it/KTW5xt

A versatile chip offers multiple applications in various electronic devices, report researchers, suggested that there is now hope that a low-powered, wireless neural implant may soon be a reality. Neural implants when embedded in the brain can alleviate the debilitating symptoms of Parkinson's…
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New research on the blood lipid-lowering protein FGF21 shows how it redistributes fatty acids by two distinct mechanisms. The discovery could lead to improved pharmaceutical treatment for type 2 diabetes and other obesity-related diseases, say researchers.
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New high-speed videos captured researchers show that as a person sneezes, they launch a sheet of fluid that balloons, then breaks apart in long filaments that destabilize, and finally disperses as a spray of droplets, similar to paint that is flung through the air.
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You know that one friend that never worries about weight and seems to stay effortlessly slim? That friend, and others like them might unknowingly possess secrets to helping those who struggle with their weight.
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An FDA-approved drug used for diabetes and obesity may also reduce cocaine dependence, new research indicates. The drug, trade name Byetta, derives from a naturally occurring hormone called glucagon-like peptide-1, or GLP-1, which regulates feeding behavior. Knowing what they did about GLP-1, the…
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An important milestone has been reached towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.
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Despite the concern of an explosion of dementia cases in an aging population over the next few decades, a new study suggests that the rate of new cases of dementia actually may be decreasing.
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Building on previous studies, researchers have demonstrated significant health improvements in the vascular system of mice following repeated treatments to remove senescent cells. They say this is the first study to show that regular and continual clearance of senescent cells improves age-related…
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In a world-first, researchers have performed cardiac MRI imaging using a 7T MRI scanner in a patient-based study. 7T MRI imaging is a powerful new technology that allows high resolution images of the beating heart, and has the capability to provide valuable information of the myocardial (heart…
http://dlvr.it/KTD6vL

DNA is unwound by a type of "pumpjack" mechanism, similar to the way one operates on an oil rig, a team of scientists suggests. This finding is based on new close-up images of the proteins that unwind DNA inside the nucleus of a yeast cell and could offer insight into ways that DNA replication can…
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People with medically serious weight problems can rarely find or have access to proven, reliable programs to help them shed pounds, new research concludes.
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In bloodhounds and neutrophils, getting the scent is not enough. Dogs and immune cells have to remember the chemoattractant they are pursuing, even when it momentarily fades out or threatens to overwhelm.
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Modern men increasingly value brains over beauty when choosing long-term mates, say researchers. While the common view is that our mate choices are evolutionarily "hardwired" in our brains and therefore minimally responsive to changing conditions, some evolutionary scientists now argue that humans…
http://dlvr.it/KTBNqV

Statin drugs interact with a gap junction protein called GJC3 that releases ATP, a major signaling molecule for inflammation in the body, new research shows. This discovery provides a significant new target in the search for why statin drugs can sometimes cause harmful effects such as muscle…
http://dlvr.it/KT8MV0

Previous research has established a link between genetic mutations in the BRCA1 and BRCA2 genes to an increased risk of developing ovarian, fallopian tube or peritoneal cancer in women. A recent publication documents the efforts of a team of researchers to determine if inherited genetic mutations…
http://dlvr.it/KT8MQp

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