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A group of biophysicists have developed a mathematical model of arterial thrombus formation, which is the main cause of heart attacks and strokes. The scientists described the process of platelet aggregation as being similar to the popular video game Tetris and derived equations that allowed them…
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In a first, researchers show the potential a PD-1 antibody, nivolumab, has in fighting the disease. Nivolumab, an inhibitory antibody for PD-1, has shown efficacy in several types of malignancies including melanoma, kidney cancer, and non-small cell lung cancer.
http://dlvr.it/CtwWMv

For many years, clinicians debated the best time to start antiretroviral therapy for HIV infection, with some worrying that the risks of treatment in terms of drug toxicities could outweigh the benefits of controlling the virus. In a new commentary, scientists argue that the results of three large…
http://dlvr.it/CtwQJt

With the aim of producing high-quality X-rays with minimal radiation exposure, particularly in children, researchers have developed a new approach to imaging patients based on the Xbox gaming system. Using proprietary software developed for the Microsoft Kinect system, researchers have adapted…
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Childbirth is arguably the most traumatic event the human body can undergo, and new imaging techniques show that up to 15 percent of women sustain pelvic injuries that don't heal.
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Certain workers' compensation (WC) policies explain much of the state-level variation in costs and outcomes of claims for low back pain (LBP), reports an American study.
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New diaphragm tissue in rats has been successfully created in the lab using a mixture of stem cells and a 3D scaffold. When transplanted, it has regrown with the same complex mechanical properties of diaphragm muscle. The study offers hope of a cure for a common birth defect and possible future…
http://dlvr.it/CtwWFn

Out of a 'haystack' of 40,000 genes from three different organisms, scientists have found genes that are involved in physical aging. If you influence only one of these genes, the healthy lifespan of laboratory animals is extended -- and possibly that of humans, too.
http://dlvr.it/Ctvtq6

Researchers have engineered changes to the revolutionary CRISPR-Cas9 genome editing system that significantly cut down on 'off-target' editing errors. The refined technique addresses one of the major technical issues in the use of genome editing.
http://dlvr.it/CtvrZT

The results of a national survey about weight loss barriers finds 90 percent of respondents discounted one of the most important factors -- your mind. A neuropsychologist says the most crucial factor is your psychological relationship with food and exercise, yet the majority (60 percent) listed…
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A sick person is obviously willing to pay for a good medical treatment, but economists have found that healthy people are potentially a much broader, if largely overlooked, market for medical innovations.
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Burnout among US physicians is getting worse. An update from a three-year study evaluating burnout and work-life balance shows that American physicians are worse off today than they were three years earlier.
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Higher taxes and prices for cigarettes are strongly associated with lower infant mortality rates in the United States, according to a new study. The association was stronger for African American infants than for non-Hispanic white infants, which has implications for trying to reduce disparities in…
http://dlvr.it/CtvCB6

Alginate forms a kind of supporting skeleton in the cell walls of certain kinds of algae. Scientists use the gel-like mass from Chilean seaweed as the substrate for stem cells. They can flexibly adjust the pore size and elasticity of the alginate, and it transports active ingredients and has better…
http://dlvr.it/Cttc3J

Despite decades of efforts to banish the idea of 'jobs for men' -- construction worker, firefighter, mechanic -- and 'jobs for women' -- teacher, flight attendant, registered nurse -- almost 69 percent of workers are in occupations that are dominated by one gender or the other. But why, asked…
http://dlvr.it/CtrNwj

Among minority women treated with early chemotherapy, black women fare worse than the other groups, new research shows. While the cause of this is not known, researchers suspect biologic differences in chemosensitivity, disparities in treatment, or socioeconomic factors that cannot be adjusted for…
http://dlvr.it/CtrQK5

A gene that, when working properly, appears to reduce the risk of heart failure and improve treatment outcomes has been identified by researchers, highlighting a possible target for the development of new drugs.
http://dlvr.it/CtrSLG

Science has a new weapon in the global war against parasitic worms that kill hundreds of thousands or people annually: xWORM. While testing various drugs, parasitologists spend interminable hours staring down microscopes, checking whether the worms are dead or alive after being exposed to the drug.…
http://dlvr.it/CtqtKj

Women with breast cancer who subsequently had a recorded diagnosis of depression had a 45% higher risk of death from all causes, according to a study. The researchers suggest this finding could help to target and support those women most at risk of depression.
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Decreases in a specific group of proteins trigger changes in the cancer microenvironment that accelerate growth and development of therapy-resistant cancer stem cells (CSCs), a team of researchers has found.
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Genetic variation in patients with inflammatory bowel disease (IBD) appears to play a major role in determining how sick they will become and could provide a road map for more effective treatments.
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Patients at safety-net hospital clinics where there was high computer use by clinicians were less likely to rate their care as excellent, according to an article.
http://dlvr.it/CtqwNV

A new genetic model has been developed that is yielding new insights into what happens when astrocytes go awry. Damage to astrocytes -- star-shaped cells found in the brain and spinal cord -- is found in many neurodegenerative conditions, but it's been unclear exactly what role astrocyte…
http://dlvr.it/CtZmv7

When public schools in Wake County, North Carolina switched from a school assignment policy based on race to one based on socioeconomic status, schools became slightly more segregated but the achievement gap lessened, according to new research.
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When preliminary tests show that a new drug has remarkable effectiveness against a lethal illness, everyone wants to know how it works. A team reports a surprising mechanism through which an important new drug against leukemia, JQ1, exerts its therapeutic effect.
http://dlvr.it/CtZMLt

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