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Researchers have developed a method for detecting single nucleotide mutations directly in the RNA of HIV, including mutations that make it resistant to some drugs. In lab tests, the single-step system performed more quickly and with better sensitivity than standard technologies.
http://dlvr.it/CSFcH2

Scientists have shown why a drug widely used to treat chemotherapy-induced anemia in ovarian and breast cancer patients also may shorten survival times in some patients by inadvertently stimulating tumor growth.
http://dlvr.it/CSFXSv

A potential new class of drugs has been discovered in mice studies that may prevent the development of temporal lobe epilepsy, one of the most common and devastating forms of epilepsy.
http://dlvr.it/CSFWp6

Researchers have discovered details of the abnormal molecular signals and biological events that drive a high-risk form of the childhood cancer neuroblastoma. Having investigated a signaling network involving three cancer-causing genes, the scientists aim to use these findings to develop more…
http://dlvr.it/CSFZTJ

Animal science researchers have identified a pair of genetic mutations that cause immune deficiencies in pigs that make them uniquely good models for testing potential medical therapies for people. The work advances previous research on pigs with severe combined immunodeficiency.
http://dlvr.it/CSFbMJ

New insights about a subset of T cells has been shared by researchers, that suggest that they appear to both inhibit cancer growth and enhance the tumor-killing powers of other immune cells.
http://dlvr.it/CSFbF7

In dream or REM sleep, brain activity is more like awake than non-REM activity, and muscles are paralyzed. Various regions of the brain affect REM sleep, but neuroscientists have found a group of neurons in the medulla that seem to play a key role. Activating them makes mice go immediately into REM…
http://dlvr.it/CSFZYH

Use of a qualification test within a retinal practice appeared to be effective in predicting which patients with intermediate age-related macular degeneration would be good candidates to initiate use of a home monitoring device for progression to more severe AMD, according to a study.
http://dlvr.it/CSFcrx

What is the future of the BRAIN Initiative? This national White House Grand Challenge involving more than 100 laboratories in the United States has already made progress in establishing large-scale neuroscience goals and developing shared tools. And now leading American neuroscientists call for the…
http://dlvr.it/CSDzv8

It's tempting to believe that people these days aren't getting enough sleep, living as we do in our well-lit houses with TVs blaring, cell phones buzzing, and a well-used coffee maker in every kitchen. But new evidence reported in Current Biology on Oct. 15 shows that three ancient groups of…
http://dlvr.it/CSDyhs

Expert advice can often be compromised by human frailties -- like their current mood or what their values are -- and should be treated accordingly, experts say.
http://dlvr.it/CSF1YC

Being able to identify a smell or flavor appears to be the most important factor in how some synesthetes 'see' them, according to a new study.
http://dlvr.it/CSF1Yh

Light has been used for the first time to activate a receptor for which the compound binding and controlling it naturally is unknown, researchers suggests. A team of scientists has now employed its novel application of optogenetics to identify a new compound that inhibits the orphan receptor ROS1,…
http://dlvr.it/CSDbTW

An international team of scientists has identified novel genes associated with chronic lymphocytic leukemia through the analysis of high-throughput sequencing data.
http://dlvr.it/CSCxwT

Survival probability of Hodgkin's lymphoma (HL) has improved significantly over the past two decades. Monoclonal antibodies against targeted proteins on Reed-Sternberg cells in HL though a popular choice for immunotherapy have yet to demonstrate complete responses. In a new study, researchers have…
http://dlvr.it/CSCyR2

People with traumatic brain injuries -- such as those incurred from violent accidents or combat -- are more prone to misjudge when faced with situations involving dispute or requiring discipline, new research indicates.
http://dlvr.it/CSCz7X

Scientists have made a breakthrough that advances our understanding of how the brain detects and prevents dehydration. The findings could have important clinical implications, as the key protein they discovered could be a target for the development of treatments and diagnostic tests for many health…
http://dlvr.it/CSCzGd

Using a sensitive new technology called single-cell RNA-seq on cells from mice, scientists have created the first high-resolution gene expression map of the newborn mouse inner ear. The findings provide new insight into how epithelial cells in the inner ear develop and differentiate into…
http://dlvr.it/CSCyrP

Yoga can help fathers in jail be better dads, new research shows.
http://dlvr.it/CSD46B

Using mouse embryos, researchers have replicated the deterioration with aging of blood stem cells, particularly red blood cells, and were able to alleviate the fetal anemia suffered by the mouse embryos and prevent death in 40 percent of the cases. This is a first step towards the development of…
http://dlvr.it/CSCQhP

A new molecule has been identified by researchers that involves skin fibrosis, a life-threatening disease characterized by the inflammation and hardening of skin tissue. The new study is the first to investigate the role of this molecule in skin fibrosis and paves the way toward new and improved…
http://dlvr.it/CSCV5P

Most patients with non-small cell lung cancer that has metastasized to the brain have a dire prognosis. But researchers have identified a subset of those patients with a rare genetic mutation who are living significantly longer than patients without the mutation.
http://dlvr.it/CSCPDm

Public access to Oxford Nanopore's MinION™ miniature sensing device has enabled an international consortium to evaluate the technology and provide a standard protocol for its use. Preliminary analysis of data generated in five very different laboratories indicates the performance and accuracy of…
http://dlvr.it/CSBn0T

Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery.
http://dlvr.it/CSBhw3

Although the public and private sectors are currently engaged in an unprecedented array of efforts to improve end-of-life care, too many of these programs are not evidence-based, says one expert. Investigators and research sponsors must be more involved to 'identify, develop and rigorously test…
http://dlvr.it/CSBhgr

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