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HIV latency depends on the activity of proteins from the human host called histone deacetylases, and previous work has shown that HDAC inhibitors can disrupt HIV latency. This study reports results from a clinical trial of an HDAC inhibitor that had shown potential in preclinical studies and…
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In-hospital nocturnal dialysis may be good for patients' hearts as well as their kidneys, a new study suggests.
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Former Canadian soldier Trevor Greene, who survived a debilitating brain injury while on duty in Afghanistan in 2006, has recovered his ability to walk again with the help of a customized exoskeleton, his personal determination and support of researchers.
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How the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study has shed light on this progression by showing the typical patterns of the brain's progression to dementia.
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Researchers have developed a model that explains how groups make collective decisions when no single member of the group has access to all possible information or the ability to make and communicate a final decision. The de-centralized decision-making model shows how positive feedback during the…
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Researchers believe that periodic clearance of a specific protein across the blood brain barrier could hold tremendous potential for new therapies.
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Taking small steps with an interactive health platform improved blood pressure, earned incentives. Eighty-five percent of the platform's most engaged users lowered their blood pressure to non-hypertensive.
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As the gap in life expectancy between the highest and lowest earners in the US has widened over time, high earners have disproportionately received larger lifetime benefits from government programs such as Social Security and Medicare, says a new congressionally mandated report.
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A deadly parasite that causes Chagas disease is widespread in a common Texas insect, according to a new study by University of Texas at El Paso (UTEP) researchers. The finding suggests that the risk of Texans contracting the disease may be higher than previously thought.
http://dlvr.it/CBsj0d

People fed beta-glucan-enriched pasta for two months showed increased populations of beneficial bacteria in their intestinal tracts, and reduced populations of non-beneficial bacteria. They also showed reduced LDL (bad) cholesterol. This work is part of a broad effort to identify potential…
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Birth control pills cause a small but significant increase in the risk of the most common type of stroke, according to a comprehensive report. Worldwide, more than 100 million women currently use oral contraceptives or have used them in the past. In the United States, there are about 40 brands of…
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A protein embedded in the surface of mitochondria -- the energy-producing batteries of living cells -- opens the door to cell death, causing cells to experience severe power failures, according to researchers. The new study suggests that blocking the door with a small molecule inhibitor could be…
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Research in rat models confirms a molecular link between activation of the amino acid response signal and the cell autophagy pathway, which is transferred from pregnant mothers' skeletal muscles to the placenta and the fetus.
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The brains of endurance trainers communicate with muscles differently than those of strength trainers or sedentary individuals, new research shows. While it is not immediately clear why the communication between the brain and muscle was different as a result of different types of exercise, one…
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For the first time, a study has identified genomic differences between the breast tumors of African American and white women, differences that could contribute to the recognized differences in recurrence rate and survival.
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A recently developed drug was significantly better at detecting recurring prostate cancer in early stages, researchers report. The American Cancer Society reports that prostate cancer is the second leading cause of cancer death in American men, behind lung cancer, with about 220,800 new cases…
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An international consortium of scientists worked to map out the antigenic differences in various strains of dengue virus. Dengue has been around for hundreds of years and has spread throughout the tropics and subtropics, and more than a third of the world's population presently lives in areas where…
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A potential new way to predict which patients with head and neck cancer may benefit most from chemotherapy has been identified by researchers. These patients commonly receive pre-treatment induction chemotherapy, before either surgery or radiotherapy, to reduce the risk of disease spread. However…
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Scientists have developed a first-of-its-kind, 3-D printed guide that helps regrow both the sensory and motor functions of complex nerves after injury. The groundbreaking research has the potential to help more than 200,000 people annually who experience nerve injuries or disease.
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A revolutionary nebulizer could one day deliver life-saving cancer drugs and vaccines traditionally given by injection. Cheap, light-weight and portable, the advanced nebuliser delivers precise drug doses to patients with life-threatening or debilitating lung conditions including cancer,…
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The global burden of a tropical disease known as leptospirosis is far greater than previously estimated, resulting in more than 1 million new infections and nearly 59,000 deaths annually, a new international study has found.
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Researchers are working on a way to use artificial intelligence to predict a patient's response to two common chemotherapy medications used to treat breast cancer -- paclitaxel and gemcitabine. They are hoping to one day remove the guesswork from breast cancer treatment with this technique.
http://dlvr.it/CBlncV

First placebo-controlled study on stress dose hydrocortisone and neurodevelopment shows that higher doses of hydrocortisone are not associated with brain injury or neurodevelopmental impairments, but may not be effective in reducing risk for bronchopulmonary dysplasia
http://dlvr.it/CBlq7j

Researchers long have known many people end cognitive behavioral therapy before the recommended course of treatment has ended, but why that happens has remained something of a mystery. New research involving patients being treated for anxiety has suggested some answers.
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A landmark clinical trial is underway, and has found that a more intensive management of high blood pressure reduces heart disease rates and saves lives.
http://dlvr.it/CBlcQd

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